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ORCID: 0000-0002-1458-9747

2023

2023
53. F. Raguseo, D. Tanase, L. Malouf, R. Rubio-Sanchez, Y. Elani, L. Di Michele*, M. Di Antonio*, The C9Orf72 hexanucleotide repeat expansion transcript forms insoluble aggregates facilitated by multimolecular G-quadruplex structuresbioRxiv, 
doi.org/10.1101/2023.01.31.526399 [PDF] [LINK]
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52. M. Walczak, L. Mancini, J. Xu, F. Raguseo, J. Kotar, P. Cicuta, L. Di Michele, A synthetic signalling network imitating the action of immune cells in response to bacterial metabolism, Adv. Mater., doi.org/10.1002/adma.202301562 (2023) [PDF] [LINK]
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51. R. Rubio-Sánchez, B.M. Mognetti, P. Cicuta, L. Di Michele, DNA-origami line-actants control domain organisation and fission in synthetic membranes, J. Am. Chem. Soc., doi.org/10.1021/jacs.3c01493 (2023) [PDF] [LINK]
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50. M. Walczak, R.A. Brady, A. Leathers, J. Kotar, L. Di Michele, Influence of hydrophobic moieties on the crystallization of amphiphilic DNA nanostructures, J. Chem. Phys., 084501 (2023). 2023 JCP Emerging Investigators Collection[PDF] [LINK]
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49. D. Morzy, C. Tekin, V. Caroprese, R. Rubio-Sánchez, L. Di Michele, M. Bastings, Interplay of mechanical and structural properties of DNA nanostructures determines their electrostatic interactions with lipid membranes, Nanoscale, 15, 2849-2859 (2023) [PDF] [LINK]
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2022

48. M. Fletcher, J. Zhu, R. Rubio-Sánchez, S.E. Sandler, K. Al Nahas, L. Di Michele, U.F. Keyser, R. Tivony, DNA-Based Optical Quantification of Ion Transport across Giant Vesicles, ACS Nano, 16(10), 17128-17138 (2022) [PDF] [LINK]
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47. A. Leathers, M. Walczak, R.A. Brady, A. Al Samad, J. Kotar, M.J. Booth, P. Cicuta,  L. Di Michele, Reaction–Diffusion Patterning of DNA-Based Artificial Cells, J. Am. Chem. Soc., 144(38), 17468–17476 (2022) [PDF] [LINK]
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46. S. Takamori, P. Cicuta*, S. Takuchi*,  L. Di Michele*, DNA-assisted selective electrofusion (DASE) of Escherichia coli and giant lipid vesicles, Nanoscale, 14, 14255 - 14267 (2022) [PDF] [LINK]
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45. M. Perez-Paez, I.A. Russell, P. Cicuta,  L. Di Michele, Modulating membrane fusion through the design of fusogenic DNA circuits and bilayer composition, Soft Matter, 18, 7035-7044 (2022). Soft Matter Emerging Investigator Series[PDF] [LINK]
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44. W.T. Kaufhold*, W. Pfeifer, C.E. Castro,  L. Di Michele, Probing the mechanical properties of DNA nanostructures with metadynamics, ACS Nano, 16(6), 8784–8797 (2022) [PDF] [LINK]
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43. G. Fabrini, A. Minard, R.A. Brady, M. Di Antonio*, L. Di Michele*, Cation-Responsive and Photocleavable Hydrogels from Noncanonical Amphiphilic DNA Nanostructures, Nano Lett., 22(2), 602–611 (2022)  [PDF] [LINK]
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2021

42. R. Rubio-Sánchez, G. Fabrini, P. Cicuta and L. Di Michele, Amphiphilic DNA Nanostructures for Bottom-Up Synthetic Biology, ChemComm,  57, 12725-12740 (2021) [PDF] [LINK]
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41. R. Rubio-Sánchez, D. O’Flaherty, A. Wang, F. Coscia, L. Di Michele, P. Cicuta, C. Bonfio, Thermal oscillations enable reshuffling of genetic material in a primitive cell cycleJ. Am. Chem. Soc. , 143(40), 16589–16598 (2021) [PDF] [LINK]
40. M. Walczak, R. Brady, L. Mancini, C. Contini, R. Rubio-Sànchez, W. Kaufhold, P. Cicuta and L. Di Michele, Responsive Core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment, Nature Comm., 12:4743 (2021) [PDF] [LINK]
39. D. Sobota+, R. Rubio-Sànchez+, H. Joshi+, A. Aksimentiev*, L. Di Michele*, and U. Keyser*, Cations Regulate membrane attachment and functionality of DNA nanostructures, J. Am. Chem. Soc., 143, 7358-7367, (2021) [PDF] [LINK]
38. R. Rubio-Sànchez, S. Eizagirre-Barke, M. Walczak, P. Cicuta and L. Di Michele, Programming the Partitioning of Amphiphilic DNA Nanostructures in Lipid Domains, Nano Lett.21, 2800–2808, (2021) [PDF] [LINK]
37. A.H. Clowsley, W.T. Kaufhold, T. Lutz A. Meletiou, L. Di Michele and C. Soeller, Repeat DNA-PAINT suppresses background and non-specific signals in optical nanoscopy, Nature Comm.,
 12:501, (2021) [PDF] [LINK]
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2020

36. R. Lanfranco, P.K. Jana, G. Bruylants, P. Cicuta, B.M. Mognetti and L. Di MicheleAdaptable DNA interactions regulate surface triggered self assembly Nanoscale, 12, 18616-18620, (2020)  [PDF] [LINK]
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35. A.H. Clowsley*, W.T. Kaufhold*, T. Lutz A. Meletiou, L. Di Michele and C. Soeller, Detecting nanoscale distribution of protein pairs by proximity-dependent super-resolution microscopyJ. Am. Chem. Soc., 142, 12069-12078, (2020) [PDF] [LINK]
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2019

34. J. del Barrio*, Ji Liu, R. A. Brady, C. S. Y. Tan, S. Chiodini, M. Ricci, R. Fernández-Leiro, C.-J. Tsai, P. Vasileiadi, L. Di Michele, D. Lairez, C. Toprakcioglu, O. A. Scherman*, Emerging Two-Dimensional Crystallization of Cucurbit[8]uril Complexes: From Supramolecular Polymers to Nanofibers, J. Am. Chem. Soc., 141(36), 14021-14025, (2019) [PDF] [LINK]
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33. B.M. Mognetti*, P. Cicuta*, and L. Di Michele*, Programmable interactions with biomimetic DNA linkers at fluid membranes and interfaces, Rep. Prog. Phys., 82, 116601, (2019) [PDF] [LINK]
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32. W.T. Kaufhold, R.A. Brady, J.M. Tuffnell, P. Cicuta, and L. Di Michele, Membrane Scaffolds Enhance the Responsiveness and Stability of DNA-Based Sensing CircuitsBioconjugate Chem.,
30, 1850-1859, (2019) [PDF] [LINK]
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31. R. Lanfranco*, P.K. Jana, L. Tunesi, P. Cicuta, B.M. Mognetti, L. Di Michele*, G. Bruylants*, Kinetics of Nanoparticle-Membrane Adhesion Mediated by Multivalent InteractionsLangmuir35(6),  2002-2012, (2019) [PDF] [LINK]
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30. E.L. Talbot, J. Kotar, L. Di Michele, P. Cicuta, Directed tubule growth from giant unilamellar vesicles in a thermal gradient, Soft Matter, 15, 1676-1683, (2019) [PDF] [LINK]
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29. R.A. Brady, W.T. Kaufhold, N.J. Brooks, V. Fodera,  L. Di Michele, Flexibility defines structure in crystals of amphiphilic DNA nanostars, J. Phys.: Cond. Matter, 31 074003, (2019). Special Issue on Emerging Leaders 2018 [PDF] [LINK] [DATASET]
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2018

28. R.A. Brady, N.J. Brooks, V. Fodera,  P. Cicuta*, L. Di Michele*, Amphiphilic-DNA Platform for the Design of Crystalline Frameworks with Programmable Structure and Functionality, J. Am. Chem. Soc.,  140(45),  15384–15392, (2018)  [PDF] [LINK] [DATASET]
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27. L. Di Michele*, P.K. Jana, B.M. Mognetti*, Steric interactions between mobile ligands facilitate complete wrapping in passive endocytosis, Phys. Rev. E, 98, 03240, (2018) [PDF] [LINK]
26. T. Lutz, A.H. Clowsely, R. Lin, S. Pagliara, L. Di Michele and C. Soeller, Versatile multiplexed super-resolution imaging of nanostructures by Quencher-Exchange-PAINTNano Research, 12, 6141–6154, (2018) [PDF] [LINK]
25. I. Jayasinghe*, A.H. Clowsley*, R. Lin, T. Lutz, C. Harrison, E. Green, D. Baddeley, L. Di Michele and C. Soeller, True molecular scale visualization of variable clustering properties of ryanodine receptorsCell Reports, 22(2), 557-567, (2018) [PDF] [LINK]

2017

24. B.C. Borro, L. Parolini, P. Cicuta, V. Fodera* and L. Di Michele*, Interaction with prefibrillar species and amyloid-like fibrils changes the stiffness of lipid bilayersPhys. Chem. Chem. Phys., 19, 27930-27934, (2017), PCCP HOT Article [PDF] [LINK]
23. S.A. Rautu, D. Orsi, L. Di Michele, G. Rowlands, P. Cicuta, and M.S. Turner, The role of optical projection in the analysis of membrane fluctuationsSoft Matter, 13, 3480-3483, (2017) [PDF] [LINK] [DATASET] 
22. R.A. Brady, N.J. Brooks, P. Cicuta, and L. Di Michele, Crystallization of amphiphilic DNA C-Stars, Nano Lett., 17(5), 3276–3281, (2017) [PDF] [LINK] [DATASET]
21. E.L. Talbot, L. Parolini, J. Kotar, L. Di Michele, and P. Cicuta, Thermophoretic migration of vesicles depends on mean temperature and head group chemistryNature Comm., 8:15351 (2017) [PDF] [LINK] [DATASET]
20. E.L. Talbot, L. Parolini, J. Kotar, L. Di Michele, and P. Cicuta, Thermal driven domain and cargo transport in lipid membranesProc. Natl. Acad. Sci. USA, 114(5) 846-851 (2017) [PDF] [LINK] [DATASET]
19. O.A. Amjad, B.M. Mognetti, P. Cicuta*, and L. Di Michele*, Membrane adhesion through bridging by multimeric ligandsLangmuir, 33(5), 1139-1146 (2017) [PDF] [LINK][DATASET]

2016

18. S.J. Bachmann, J. Kotar, A. Saric, P. Cicuta, L. Di Michele* and B.M. Mognetti*, Melting transition in lipid vesicles functionalised by mobile DNA linkersSoft Matter, 12(37), 7804-7817 (2016) [PDF] [LINK] [DATASET]
17. L. Di Michele, S.J. Bachmann, L. Parolini, and B. M. Mognetti, Communication: Free energy of ligand-receptor systems forming multimeric complexesJ. Chem. Phys., 144(16), 161104, (2016) [PDF] [LINK]
16. L. Parolini, J. Kotar, L. Di Michele*, and B. M. Mognetti*, Controlling self-assembly kinetics of DNA-functionalized liposomes using toehold exchange mechanismACS Nano, 10(2), 2392-2398, (2016) [PDF] [LINK] [DATASET]

2015

15. S. F. Shimobayashi, B. M. Mognetti, L. Parolini, D. Orsi, P. Cicuta, and L. Di Michele, Direct measurement of DNA-mediated adhesion between lipid bilayersPhys. Chem. Chem. Phys., 15(9), 3115-3129, (2015)  [PDF] [LINK]
14. A. Zaccone, I. Terentjev, L. Di Michele, E. M. Terentjev, Fragmentation and depolymerization of non-covalently bonded filamentsJ. Chem. Phys., 142, 114905, (2015) [PDF] [LINK]
13. L. Parolini, B. M. Mognetti, J. Kotar, E. Eiser, P. Cicuta, and L. Di Michele, Volume and porosity thermal regulation in lipid mesophases by coupling mobile ligands to soft membranesNature Comm., 6:5948 (2015) [PDF] [LINK]

2014

12. L. Di Michele*, B. M. Mognetti*, T. Yanagishima, P. Varilly, Z. Ruff, D. Frenkel, and E. Eiser, Effect of inert tails on the thermodynamics of DNA hybridizationJ. Am. Chem. Soc., 136(18), 6538-6541, (2014) [PDF] [LINK]
11. L. Di Michele*, D. Fiocco*, F. Varrato*, S. Sastry, E. Eiser, and G. Foffi, Aggregation dynamics, structure, and mechanical properties of bigelsSoft Matter, 10, 3633-3648, (2014) [PDF] [LINK]
10. L. Di Michele, E. Eiser and V. Foderà, Minimal Model for Self-Catalysis in the Formation of Amyloid-Like Elongated FibrilsJ. Phys. Chem. Lett., 4 3158-3164, (2013) [PDF] [LINK]

2013

9. L. Di Michele, F. Varrato, J. Kotar, S. H. Nathan, G. Foffi and E. Eiser, Multistep kinetic self-Assembly of DNA-coated colloidsNature Comm., 4:2007, (2013) [PDF] [LINK]
8. L. Di Michele and E. Eiser, Developments in Understanding and controlling self assembly of DNA-functionalized colloidsPhys. Chem. Chem. Phys., 15, 3115-3129, (2013) [PDF] [LINK]

2012

7. F. Varrato, L. Di Michele, M. Belushkin, N. Dorsaz, S. H. Nathan, E. Eiser and G. Foffi, Arrested demixing opens route to bigelsProc. Natl. Acad. Sci. USA, 109(47), 19155-19160, (2012) [PDF] [LINK]
6. L. Di Michele, A. Zaccone and E. Eiser, Analytical theory of polymer-network-mediated interactions between colloidal particlesProc. Natl. Acad. Sci. USA, 109(26), 10187-10192, (2012) [PDF] [LINK]
5. T. Yanagishima, L. Di Michele, J. Kotar and E. Eiser, Diffusive behavior of PLL-PEG coated colloids on λ-DNA brushes - Tuning hydrophobicitySoft Matter, 8(25), 2792-2798, (2012) [PDF] [LINK]

2011

4. L. Di Michele, T. Yanagishima, A. R. Brewer, J. Kotar,  E. Eiser and S. Fraden, Interactions between colloids induced by a soft cross-linked polymer substratePhys. Rev. Lett., 107(13), 136101 (2011) [PDF] [LINK]
3. L. Di Michele, C. Shelly, P. De Marco, P. See, D. Cox and O. Kazakova, Detection and susceptibility measurement of a single dynal beadJ. Appl. Phys., 110(6), 063916 (2011) [PDF] [LINK]

2010

2. L. Di Michele, C. Shelly, J. Gallop and O. Kazakova, Single Particle Detection: Phase control in submicron Hall sensorsJ. Appl. Phys., 108(10), 103918 (2010) [PDF] [LINK]
1. A. Filipponi, L. Di Michele and C. Ferrante, Viscoelastic behavior of a mass-rubber band oscillator, Am. J. Phys., 78(4), 437-444 (2010) [PDF] [LINK]
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