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Publications

Check Lorenzo's Google Scholar page for an up to date list

64

D. A. Tanase, D. Osmanovic, R. Rubio-Sanchez, L. Malouf, E. Franco, L. Di Michele*, Internal phase separation in synthetic DNA condensatesbioRxiv

doi.org/10.1101/2025.03.19.644034, (2025) [LINK]

62

E. Lučinskaitė, A. F. E. Bokhobza, A. Stannard, A. Meletiou, C. Estell, S. West, L. Di Michele, C. Soeller*, A. H. Clowsley*, Reduced Non‐Specific Binding of Super‐Resolution DNA‐PAINT Markers by Shielded DNA‐PAINT Labeling Protocols, Small, 20(51), 2405032 (2024) [LINK]

61

J. Bucci, L. Malouf, D. A. Tanase, N. Farag, J. R. Lamb, R. Rubio-Sánchez, S. Gentile, E. Del Grosso, C. F. Kaminski, L. Di Michele*, F. Ricci*, Enzyme-responsive RNA condensates, J. Am. Chem. Soc., 146(46), 31529–31537 (2024) [LINK]

60

J. M. Stewart, S. Li, A. A. Tang, M. A. Klocke, M. V. Gobry, G. Fabrini, L. Di Michele, P. W. K. Rothemund*, E. Franco*, Modular RNA motifs for orthogonal phase separated compartments, Nat. Commun., 15:6244 (2024) [LINK]

59

G. Fabrini, N. Farag, S. P. Nuccio, S. Li, J. M. Stewart, A. A Tang, R. McCoy, R. M. Owens, P. W. K. Rothemund, E. Franco, M. Di Antonio, L. Di Michele*, Co-transcriptional production of programmable RNA condensates and synthetic organelles, Nat. Nanotech., 19, 1665–1673 (2024) [LINK]

58

L. Malouf, D. A. Tanase, L. Di Michele*, Synthetic Condensates and Cell-Like Architectures from Amphiphilic DNA Nanostructures, J. Vis. Exp., 207, e66738 (2024) [LINK]

57

E. Ward*, R. McClelland, J. Lamb, R. Rubio-Sanchez, C. Christensen, L. Di Michele, G. Kaminski-Schierle, C. Kaminski, Fast, multicolour optical sectioning over extended fields of view with patterned illumination and machine learning, Biomed. Optics Express, 15, 1074-1088

 (2024) [LINK]

56

Z. Peng, S. Iwabuchi, K. Izumi, S. Takiguchi, M. Yamaji, S. Fujita, H. Suzuki, F. Kambara, G. Fukasawa, A. Cooney, L. Di Michele*, Y. Elani*, T. Matsuura*, R. Kawano*, Modular RNA motifs for orthogonal phase separated compartments, Lab Chip, 24, 996-1029 (2024) [LINK]

55

F. Raguseo, D. Tanase, L. Malouf, R. Rubio-Sanchez, Y. Elani, L. Di Michele*, M. Di Antonio*, The C9Orf72 hexanucleotide repeat expansion transcript forms insoluble aggregates facilitated by multimolecular G-quadruplex structures, Nat. Commun., 14:8272 (2023) [LINK]

54

C. Dinet , A. Torres-Sánchez , R. Lanfranco , L. Di Michele, M. Arroyo* and M. Staykova*, Patterning and dynamics of membrane adhesion under hydraulic stress, Nat. Commun., 14:7445 (2023) [LINK]

53

L. Malouf, D. A. Tanase, G. Fabrini, R. A. Brady, M. Paez-Perez, A. Leathers, M. J. Booth, L. Di Michele*, Sculpting DNA-based synthetic cells through phase separation and phase-targeted activity, Chem, 9(11), 3347-3364 (2023) [LINK]

52

M. Walczak, L. Mancini, J. Xu, F. Raguseo, J. Kotar, P. Cicuta, L. Di Michele*, A synthetic signalling network imitating the action of immune cells in response to bacterial metabolismAdv. Mater., 17, 2301562 (2023) [LINK]

51

R. Rubio-Sánchez, B.M. Mognetti, P. Cicuta, L. Di Michele*, DNA-origami line-actants control domain organisation and fission in synthetic membranesJ. Am. Chem. Soc.15(20), 11265–11275 (2023) [LINK]

50

M. Walczak, R.A. Brady, A. Leathers, J. Kotar, L. Di Michele*, Influence of hydrophobic moieties on the crystallization of amphiphilic DNA nanostructures, J. Chem. Phys., 084501 (2023) [LINK]

49

D. Morzy, C. Tekin, V. Caroprese, R. Rubio-Sánchez, L. Di Michele, M. Bastings*, Interplay of mechanical and structural properties of DNA nanostructures determines their electrostatic interactions with lipid membranesNanoscale, 15, 2849-2859 (2023) [LINK]

48

M. Fletcher, J. Zhu, R. Rubio-Sánchez, S.E. Sandler, K. Al Nahas, L. Di Michele, U.F. Keyser, R. Tivony*, DNA-Based Optical Quantification of Ion Transport across Giant Vesicles, ACS Nano, 16(10), 17128-17138 (2022) [LINK]

47

A. Leathers, M. Walczak, R.A. Brady, A. Al Samad, J. Kotar, M.J. Booth, P. Cicuta,  L. Di Michele*, Reaction–Diffusion Patterning of DNA-Based Artificial CellsJ. Am. Chem. Soc., 144(38), 17468–17476 (2022)  [LINK]

46

S. Takamori, P. Cicuta*, S. Takuchi*,  L. Di Michele*, DNA-assisted selective electrofusion (DASE) of Escherichia coli and giant lipid vesiclesNanoscale, 14, 14255-14267 (2022) [LINK]

45

M. Perez-Paez, I.A. Russell, P. Cicuta,  L. Di Michele*, Modulating membrane fusion through the design of fusogenic DNA circuits and bilayer compositionSoft Matter, 18, 7035-7044 (2022) [LINK]

44

W.T. Kaufhold*, W. Pfeifer, C.E. Castro,  L. Di Michele*, Probing the mechanical properties of DNA nanostructures with metadynamicsACS Nano, 16(6), 8784–8797 (2022) [LINK]

43

G. Fabrini, A. Minard, R.A. Brady, M. Di Antonio*, L. Di Michele*, Cation-Responsive and Photocleavable Hydrogels from Noncanonical Amphiphilic DNA Nanostructures, Nano Lett., 22(2), 602–611 (2022) [LINK]

42

R. Rubio-Sánchez, G. Fabrini, P. Cicuta and L. Di Michele, Amphiphilic DNA Nanostructures for Bottom-Up Synthetic BiologyChemComm,  57, 12725-12740 (2021) [LINK]

41

R. Rubio-Sánchez, D. O’Flaherty, A. Wang, F. Coscia, L. Di Michele, P. Cicuta, C. Bonfio*, Thermal oscillations enable reshuffling of genetic material in a primitive cell cycleJ. Am. Chem. Soc., 143(40), 16589–16598 (2021) [LINK]

40

M. Walczak, R. Brady, L. Mancini, C. Contini, R. Rubio-Sànchez, W. Kaufhold, P. Cicuta and L. Di Michele*, Responsive Core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapmentNat. Commun., 12:4743 (2021) [LINK]

39

D. Sobota, R. Rubio-Sànchez, H. Joshi, A. Aksimentiev*, L. Di Michele*, and U. Keyser*, Cations Regulate membrane attachment and functionality of DNA nanostructuresJ. Am. Chem. Soc., 143, 7358-7367, (2021) [LINK]

38

R. Rubio-Sànchez, S. Eizagirre-Barke, M. Walczak, P. Cicuta and L. Di Michele*, Programming the Partitioning of Amphiphilic DNA Nanostructures in Lipid DomainsNano Lett., 21, 2800–2808, (2021) [LINK]

37

A.H. Clowsley, W.T. Kaufhold, T. Lutz A. Meletiou, L. Di Michele and C. Soeller*, Repeat DNA-PAINT suppresses background and non-specific signals in optical nanoscopyNat. Commun.,
12:501, (2021) [LINK]

36

R. Lanfranco, P.K. Jana, G. Bruylants, P. Cicuta, B.M. Mognetti and L. Di Michele*, Adaptable DNA interactions regulate surface triggered self assembly, Nanoscale, 12, 18616-18620, (2020) [LINK]

35

A.H. Clowsley*, W.T. Kaufhold*, T. Lutz A. Meletiou, L. Di Michele and C. Soeller*, Detecting nanoscale distribution of protein pairs by proximity-dependent super-resolution microscopyJ. Am. Chem. Soc., 142, 12069-12078, (2020) [LINK]

34

J. del Barrio*, J. Liu, R. A. Brady, C. S. Y. Tan, S. Chiodini, M. Ricci, R. Fernández-Leiro, C.-J. Tsai, P. Vasileiadi, L. Di Michele, D. Lairez, C. Toprakcioglu, O. A. Scherman*, Emerging Two-Dimensional Crystallization of Cucurbit[8]uril Complexes: From Supramolecular Polymers to NanofibersJ. Am. Chem. Soc., 141(36), 14021-14025, (2019) [LINK]

33

B.M. Mognetti*, P. Cicuta*, and L. Di Michele*, Programmable interactions with biomimetic DNA linkers at fluid membranes and interfacesRep. Prog. Phys., 82, 116601, (2019) [LINK]

32

W.T. Kaufhold, R.A. Brady, J.M. Tuffnell, P. Cicuta, and L. Di Michele*, Membrane Scaffolds Enhance the Responsiveness and Stability of DNA-Based Sensing Circuits, Bioconjugate Chem.,
30, 1850-1859, (2019) [LINK]

31

R. Lanfranco*, P.K. Jana, L. Tunesi, P. Cicuta, B.M. Mognetti, L. Di Michele*, G. Bruylants*, Kinetics of Nanoparticle-Membrane Adhesion Mediated by Multivalent InteractionsLangmuir, 35(6),  2002-2012, (2019) [LINK]

30

E.L. Talbot, J. Kotar, L. Di Michele, P. Cicuta*, Directed tubule growth from giant unilamellar vesicles in a thermal gradient, Soft Matter, 15, 1676-1683, (2019) [LINK]

29

R.A. Brady, W.T. Kaufhold, N.J. Brooks, V. Fodera,  L. Di Michele, Flexibility defines structure in crystals of amphiphilic DNA nanostarsJ. Phys.: Cond. Matter, 31 074003, (2019) [LINK]

28

R.A. Brady, N.J. Brooks, V. Fodera,  P. Cicuta*, L. Di Michele*, Amphiphilic-DNA Platform for the Design of Crystalline Frameworks with Programmable Structure and FunctionalityJ. Am. Chem. Soc.,  140(45), 15384–15392, (2018) [LINK]

27

L. Di Michele*, P.K. Jana, B.M. Mognetti*, Steric interactions between mobile ligands facilitate complete wrapping in passive endocytosisPhys. Rev. E, 98, 03240, (2018) [LINK]

26

T. Lutz, A.H. Clowsely, R. Lin, S. Pagliara, L. Di Michele and C. Soeller, Versatile multiplexed super-resolution imaging of nanostructures by Quencher-Exchange-PAINTNano Research, 12, 6141–6154, (2018) [LINK]

25

I. Jayasinghe*, A.H. Clowsley*, R. Lin, T. Lutz, C. Harrison, E. Green, D. Baddeley, L. Di Michele and C. Soeller*, True molecular scale visualization of variable clustering properties of ryanodine receptorsCell Reports, 22(2), 557-567, (2018) [LINK]

24

B.C. Borro, L. Parolini, P. Cicuta, V. Fodera* and L. Di Michele*, Interaction with prefibrillar species and amyloid-like fibrils changes the stiffness of lipid bilayersPhys. Chem. Chem. Phys., 19, 27930-27934, (2017) [LINK]

23

S.A. Rautu, D. Orsi, L. Di Michele, G. Rowlands, P. Cicuta, and M.S. Turner*, The role of optical projection in the analysis of membrane fluctuationsSoft Matter, 13, 3480-3483, (2017) [LINK]

22

R.A. Brady, N.J. Brooks, P. Cicuta, and L. Di Michele, Crystallization of amphiphilic DNA C-StarsNano Lett., 17(5), 3276–3281, (2017) [LINK]

21

E.L. Talbot, L. Parolini, J. Kotar, L. Di Michele, and P. Cicuta*, Thermophoretic migration of vesicles depends on mean temperature and head group chemistryNat. Commun., 8:15351 (2017) [LINK]

20

E.L. Talbot, L. Parolini, J. Kotar, L. Di Michele, and P. Cicuta*, Thermal driven domain and cargo transport in lipid membranesProc. Natl. Acad. Sci. USA, 114(5) 846-851 (2017) [LINK]

19

O.A. Amjad, B.M. Mognetti, P. Cicuta*, and L. Di Michele*, Membrane adhesion through bridging by multimeric ligandsLangmuir, 33(5), 1139-1146 (2017) [LINK]

18

S.J. Bachmann, J. Kotar, A. Saric, P. Cicuta, L. Di Michele* and B.M. Mognetti*, Melting transition in lipid vesicles functionalised by mobile DNA linkersSoft Matter, 12(37), 7804-7817 (2016) [LINK]

17

L. Di Michele, S.J. Bachmann, L. Parolini, and B. M. Mognetti, Communication: Free energy of ligand-receptor systems forming multimeric complexesJ. Chem. Phys., 144(16), 161104, (2016) [LINK]

16

L. Parolini, J. Kotar, L. Di Michele*, and B. M. Mognetti*, Controlling self-assembly kinetics of DNA-functionalized liposomes using toehold exchange mechanismACS Nano, 10(2), 2392-2398, (2016) [LINK]

15

S. F. Shimobayashi, B. M. Mognetti, L. Parolini, D. Orsi, P. Cicuta, and L. Di Michele, Direct measurement of DNA-mediated adhesion between lipid bilayersPhys. Chem. Chem. Phys., 15(9), 3115-3129, (2015) [LINK]

14

A. Zaccone, I. Terentjev, L. Di Michele, E. M. Terentjev, Fragmentation and depolymerization of non-covalently bonded filamentsJ. Chem. Phys., 142, 114905, (2015) [LINK]

13

L. Parolini, B. M. Mognetti, J. Kotar, E. Eiser, P. Cicuta, and L. Di Michele, Volume and porosity thermal regulation in lipid mesophases by coupling mobile ligands to soft membranesNat. Commun., 6:5948 (2015) [LINK]

12

L. Di Michele*, B. M. Mognetti*, T. Yanagishima, P. Varilly, Z. Ruff, D. Frenkel, and E. Eiser, Effect of inert tails on the thermodynamics of DNA hybridizationJ. Am. Chem. Soc., 136(18), 6538-6541, (2014) [LINK]

11

L. Di Michele*, D. Fiocco*, F. Varrato*, S. Sastry, E. Eiser, and G. Foffi, Aggregation dynamics, structure, and mechanical properties of bigels, Soft Matter, 10, 3633-3648, (2014) [LINK]

10

L. Di Michele, E. Eiser and V. Foderà, Minimal Model for Self-Catalysis in the Formation of Amyloid-Like Elongated FibrilsJ. Phys. Chem. Lett., 4 3158-3164, (2013) [LINK]

9

L. Di Michele, F. Varrato, J. Kotar, S. H. Nathan, G. Foffi and E. Eiser, Multistep kinetic self-Assembly of DNA-coated colloidsNat. Commun., 4:2007, (2013) [LINK]

8

L. Di Michele and E. Eiser, Developments in Understanding and controlling self assembly of DNA-functionalized colloids, Phys. Chem. Chem. Phys., 15, 3115-3129, (2013) [LINK]

7

F. Varrato, L. Di Michele, M. Belushkin, N. Dorsaz, S. H. Nathan, E. Eiser and G. Foffi, Arrested demixing opens route to bigelsProc. Natl. Acad. Sci. USA, 109(47), 19155-19160, (2012) [LINK]

6

L. Di Michele, A. Zaccone and E. Eiser, Analytical theory of polymer-network-mediated interactions between colloidal particlesProc. Natl. Acad. Sci. USA, 109(26), 10187-10192, (2012) [LINK]

5

T. Yanagishima, L. Di Michele, J. Kotar and E. Eiser, Diffusive behavior of PLL-PEG coated colloids on λ-DNA brushes - Tuning hydrophobicitySoft Matter, 8(25), 2792-2798, (2012) [LINK]

4

L. Di Michele, T. Yanagishima, A. R. Brewer, J. Kotar,  E. Eiser and S. Fraden, Interactions between colloids induced by a soft cross-linked polymer substratePhys. Rev. Lett., 107(13), 136101 (2011) [LINK]

3

L. Di Michele, C. Shelly, P. De Marco, P. See, D. Cox and O. Kazakova, Detection and susceptibility measurement of a single dynal beadJ. Appl. Phys., 110(6), 063916 (2011) [LINK]

2

L. Di Michele, C. Shelly, J. Gallop and O. Kazakova, Single Particle Detection: Phase control in submicron Hall sensorsJ. Appl. Phys., 108(10), 103918 (2010) [LINK]

1

 A. Filipponi, L. Di Michele and C. Ferrante, Viscoelastic behavior of a mass-rubber band oscillatorAm. J. Phys., 78(4), 437-444 (2010) [LINK]

Contacts

Email:

ld389[at]cam.ac.uk

@DiMicheleLab1

@dimichelelab1.bsky.social

Department of Chemical Engineering and Biotechnology,

University of Cambridge

Philippa Fawcett Drive

Cambridge CB3 0AS

United Kingdom 

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